Post-doctoral Fellow for the Structural Biology Group

Context & Job description

As part of the Extremely Brilliant Source facility upgrade (, the ESRF is constructing a new beamline for serial and time-resolved macromolecular crystallography (TR-)SSX experiments at room temperature. The new ID29 beamline will deliver an unprecedented flux density, allowing the recording of diffraction data from micron-sized samples in a few microseconds, and will be equipped with a next generation diffractometer and a Jungfrau detector. Beamline operations will be supported by a dedicated sample preparation laboratory where the most suitable crystal delivery systems such as injectors, fixed targets and microfluidic devices will be prepared and characterised prior to experiments.

The postdoctoral position available will focus on developing novel sample environments, delivery systems and data collection methods for (TR-SSX). These will, initially, be tested and commissioned at other ESRF MX microfocus beamlines. The selected candidate will also take part in the commissioning of the new ID29, performing state-of-the art experiments at the new end-station.

As for all post-doctoral researchers in the Structural Biology Group, the successful candidate will participate in in-house research programmes, will contribute to the operation of the beamline and will provide support to external users as local contact. He/She will also have the opportunity to develop his/her own research programme.

Further information may be obtained from Daniele de Sanctis (tel.: +33 (0)4 76 88 28 69, email:

Expected profile

  • PhD in chemistry, physics, biophysics, biology or closely related science obtained less than 3 years ago
  • A strong background in X-ray crystallography and serial crystallography is desirable
  • A strong interest in new method development
  • Ability to interact with multi-disciplinary staff and facility users
  • Proficiency in English (working language at the ESRF)

Working conditions

Contract of 18 months, renewable for a further 6 to 18-month period.

We offer a comprehensive benefits package designed to support your quality of life and your installation in the Grenoble area when relocation is needed.

The annual gross salary may be completed by additional allowances (shift allowance, standby allowance, expatriation allowance, etc.).


Company description

The European Synchrotron, the ESRF, is an international research centre based in Grenoble, France.

Through its innovative engineering, pioneering scientific vision and a strong commitment from its 700 staff members, the ESRF is recognised as one of the top research facilities worldwide. Its particle accelerator produces intense X-ray beams that are used by thousands of scientists each year for experiments in diverse fields such as biology, medicine, environmental sciences, cultural heritage, materials science, and physics.

Supported by 22 countries, the ESRF is an equal opportunity employer and encourages diversity.

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