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PhD student at ESRF - studying mineral-protein superlattices in silica sponges

Context & Job description

Thesis subject: Mineral-Protein Superlattices in Silica Sponges.

We are seeking a highly motivated student to contribute to an exciting interdisciplinary research project on the ID01 beamline in collaboration with the Technische Universität Dresden (TUD). This project aims to understand the biomineralization mechanisms that lead to the formation of highly ordered silica structures in marine sponges, bridging concepts from physics, materials science, and biology.

Key Responsibilities:

(1) Conduct X-ray diffraction (BCDI) and electron microscopy experiments to analyze the crystalline structure and strain distribution of protein-superlattices in sponge spicules.

(2) Develop and refine multi-BCDI measurement protocols for imaging hybrid protein-mineral structures.

(3) Collaborate with experts from ESRF, TUD, and Weizmann Institute, integrating findings into a geometric frustration model that explains lattice distortions and branching mechanisms.

(4) Analyze experimental data using advanced computational tools and present results in research meetings and scientific publications.

Further information may be obtained from Dr. Steven Leake (tel.: +33 (0)4 38 88 19 39, email: leake@esrf.fr) and Dr. Igor Zlotnikov (email: igor.zlotnikov@tu-dresden.de)

Expected profile

• Degree allowing enrolment for a PhD (such as MSc, Master 2 de Recherche, Laurea or equivalent) in chemistry, materials science, physics or a closely related science. However minimum degree level may vary between universities.

• A background in bioengineering/ physics/ crystallography is desirable.

• Manual skills and a keen attention to detail are essential in this work environment, including both laboratory work and beamline operations.

• The ability/ willingness to code (Python) is mandatory, data mining is critical to the success of this project.

• Proficiency in English (A proof of upper-intermediate B2 level must be included in the application. Applicants originating from native-English-speaking countries can apply without the need for proof of level. An official degree conducted in English will be also accepted as a proof). If the applicant is unable to provide proof, an English test (free of charge) will be requested.

• Compliance with the Marie Sklodowska-Curie mobility rule: candidates may not have resided or carried out their main activity (work, studies, etc.) in the host institute’s country for more than twelve months in the three years immediately before the application deadline.

• All researchers recruited must be doctoral candidates, i.e. not already working towards or in possession of a doctoral degree at the date of the recruitment.

• Candidates must satisfy the conditions for enrolment in a doctoral programme.

Working conditions

The successful candidate will be enrolled in the doctoral school at Technische Universität Dresden — TU Dresden (TUD), Germany, and based full-time at the ESRF (Grenoble, France), other than a 3-month secondment at TUD (Dresen, Germany). Additional visits totalling no more than 3 months may be made to the University of Dresden when needed. Furthermore, a varied pedagogical training programme will be offered to the successful candidate throughout the 3-year PhD project.

Do you recognize yourself in this description? Apply now for your next professional adventure!

What we offer:

  1. Join an innovative international research institute, with a workforce from 38 different countries
  2. Collaborate with global experts to advance science and address societal challenges
  3. Come and live in a vibrant city, in the heart of the Alps, and Europe's Green Capital 2022
  4. Enjoy a workplace designed to support your quality of life
  5. Benefit from our competitive compensation and allowances package, including financial support for your relocation to Grenoble

For further information on employment terms and conditions, please refer to https://www.esrf.fr/home/Jobs/what-we-offer.html

The ESRF is an equal opportunity employer and encourages applications from disabled persons.

Company description

More details about the Nextstep Doctoral Programme on www.nextstep-programme.eu

NEXTSTEP will train 36 enthusiastic researchers to exploit the unique and transversal capabilities of analytical research infrastructures in tackling the challenges associated with sustainable development and industrial competitiveness in the areas of “Health”, “Digital, Industry & Space”, “Climate, Energy and Mobility” and “Food, Bioeconomy, Natural Resources, Agriculture and Environment”, which are at the heart of Horizon Europe. Host laboratories: ESRF and ILL (France), FZJ (Germany), AREA (Italy), NTNU (Norway).

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